Pharmacy and drug delivery systems

The analysis of tablets, drug-coated stents, and other drug delivery systems requires the determination of the atomic as well as the molecular composition of the sample with high lateral and depth resolution. In addition to the active pharmaceutical ingredients, the excipients and matrix materials have to be detected. Common questions include:

• Structure elucidation of active pharmaceutical ingredients
• Distribution of active ingredients and excipients in tablets (incl. galenic investigation)
• Depth distribution of active ingredients in coated stents
• Discoloration on and in tablets
• Characterization of impurities in tablets
• Layer structure of drug delivery systems
• Drug diffusion in controlled delivery systems
• Impurities from blister packaging